Péptidos

Lipoamido-dPEG®8-Acid is a PEG molecule conjugated with a lipid moiety. Lipoamido-dPEG®8-Acid, conjugated to this lipid constituent, is very important especially in drug delivery and vaccine development as it helps improve the stability and circulation time of lipid nanoparticles (LNPs) and liposomes.

Angiotensin IV (Human) is a peptide hormone and peptidase inhibitor that belongs to the family of angiotensins. It is produced by the renin-angiotensin system and inhibits the action of angiotensin converting enzyme, an enzyme that converts angiotensin I into angiotensin II. Angiotensin IV has been used for research purposes as well as for therapeutic applications in cardiovascular diseases, hypertension, and congestive heart failure. Angiotensin IV is a high purity product with a purity greater than 99%.

Somatostatin is a peptide hormone that has been found to inhibit pituitary growth hormone release as well as endocrine, pancreatic and GI secretions. It is widely expressed throughout the body for example in the gastrointestinal (GI) tract, hypothalamus, pancreas and the central nervous system. In the central nervous system somatostatin plays a role in neurotransmission modification and it has also demonstrated to be effective against a number of cancers such as squamous carcinoma. This product contains disulfide bonds between Cys3-Cys14 and is available as a 0.5mg vial.

Secretin (human) is a peptide hormone that is produced in the duodenum and is involved in the regulation of pancreatic bicarbonate, gastric acid and osmoregulation. Secretin binds to secretin receptors which are G-protein coupled receptors and are expressed in pancreatic centroacinar cells. Secretin binds to these receptors and activates adenylate cyclase which converts ATP into cAMP which results in the secretion of bicarbonate from the pancreas. Secretin plays a role in osmoregulation through its effects on the kidney, pituitary gland and the hypothalamus. This product is available as a 0.5mg vial.

Melanin-concentrating hormone (MCH) is a neuropeptide that is used to study the regulation of food intake and body weight. MCH binds to its receptor, the melanocortin-4 receptor (MC4R), which is coupled to an ion channel. This binding causes the release of potassium ions from cells, leading to depolarization and increased neuronal excitability. It has been shown that MCH can be used as a research tool for studying ion channels, ligand-receptor interactions, and cell biology.

A synthetic peptide for use as a blocking control in assays to test for specificity of HNRPDL antibody, catalog no. 70R-1322

Bis-dPEG®17-NHS Ester is a PEG polymer categorised as homobifunctional PEG (X-PEG X). Used as a linker, bis-dPEG®17-NHS Ester is used to attached PEG to proteins, peptides, oligonucleotides, nanoparticles and small molecules via pegylation, a bioconjugation technique.

A synthetic peptide for use as a blocking control in assays to test for specificity of VSIG1 antibody, catalog no. 70R-7017

A synthetic peptide for use as a blocking control in assays to test for specificity of SLC10A1 antibody, catalog no. 70R-7046

A synthetic peptide for use as a blocking control in assays to test for specificity of KIF5B antibody, catalog no. 70R-5599

A synthetic peptide for use as a blocking control in assays to test for specificity of MFI2 antibody, catalog no. 70R-10040

A synthetic peptide for use as a blocking control in assays to test for specificity of PPFIBP1 antibody, catalog no. 70R-1229

Aminooxy-dPEG®12-amido-dPEG®12-(m-dPEG®11)3 is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. Aminooxy-dPEG®12-amido-dPEG®12-(m-dPEG®11)3 is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

TFP-dPEG®12-Biotinidase Resistant Biotin is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. TFP-dPEG®12-Biotinidase Resistant Biotin is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

Poly-L-Lysine Hydrochloride is a synthetic polymer that has been shown to inhibit the growth of cancer cells. It has also been shown to be effective in preventing neuronal cell death, as well as toxicity caused by exposure to high levels of water vapor. Poly-L-Lysine Hydrochloride can be used as an anticancer agent and has a synergistic effect with other drugs. This polymer is thought to work by blocking the synthesis of DNA, RNA, and proteins, which are vital for the cell's survival.

Amino-dPEG®4-t-Butyl Ester is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. Amino-dPEG®4-t-Butyl Ester is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

Amylin is a peptide that belongs to the group of activators. It has been shown to be an inhibitor of ion channels, and has also been demonstrated to activate cell signaling pathways. Amylin can be used as a research tool for studying protein interactions, receptor ligands, and pharmacology. Amylin can be used in antibody production or as a high-purity reagent for life science or cell biology applications.

Azido-dPEG®4-NHS ester is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. Azido-dPEG®4-NHS ester is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

Met-Met is a dipeptide that is synthesized from the amino acids methionine and methyltetrahydrofolate. It is used in the synthesis of peptides and biochemicals, as well as in pharmacological treatments for diseases including bacterial infections. Met-Met has significant interactions with dopamine, catechol-o-methyltransferase, and energy metabolism. The enzyme catechol-o-methyltransferase catalyzes the conversion of dopamine to 3,4-dihydroxyphenylacetic acid (DOPAC), which may lead to a decrease in dopamine levels. Met-Met also inhibits the metabolism of catecholamines, leading to an increase in cellular levels of catecholamines such as dopamine and norepinephrine. This inhibition may be responsible for metabolic disorders such as obesity or low body mass index (BMI)

Bz-Arg-AMC is a fluorescent probe that binds to the nicotinic acetylcholine receptor (nAChR) in the presence of calcium ions and emits light when excited by ultraviolet light. It can be used to study the activation of nAChRs, as well as their interactions with other proteins such as peptides. Bz-Arg-AMC has a molecular weight of 551.9 g/mol, with a purity of > 98% and an optical purity of > 99%. This product can be used for research purposes only, not for diagnostic or therapeutic purposes.