Péptidos

PDGF BB is a cytokine that is produced by macrophages and fibroblasts in response to an immune stimulus. PDGF BB signals through the PDGF receptor and has been shown to be involved in the development of atherosclerosis. Cytokines are also proteins that are released by cells as a response to an external stimulus and can promote cell growth, differentiation, or suppress cell death. Cytokines play a role in the inflammatory process, regulation of immune responses, and other biological processes. Cytokine production is regulated by various factors including cytokine receptors, cytokine synthesis, gene expression, and post-translational modifications. Escherichia coli (E. coli) is a bacterium that belongs to the family Enterobacteriaceae and causes infection in humans. E. coli can produce toxins that cause diarrhea or other symptoms of food poisoning in humans. Cytokines have been shown to regulate E. coli growth

Maltose Binding Protein E.coli Recombinant is a maltose binding protein derived from E. coli that can be used as a research tool in pharmacology and cell biology. Maltose Binding Protein E.coli Recombinant is an antibody that binds to the maltose receptor on the surface of cells, which are found on the outer membrane of most bacteria. Maltose Binding Protein E.coli Recombinant is a high-purity recombinant protein with a molecular weight of about 31 kDa, and has been shown to be an activator and inhibitor of ion channels, depending on its concentration. This protein also interacts with various proteins in the cytoplasm and binds to peptides that have been identified as ligands for this receptor.

This product is a Fibrinogen Heavy Tryptic Peptide Standard for protein identification and quantitation. Fibrinogen is glycoprotein produced by the liver and is a precursor to fibrin which makes up blood clots.

Ac-Lys-Val-Pro-Leu-ACC is a peptide used as a research tool to study protein interactions. Ac-Lys-Val-Pro-Leu-ACC binds to the extracellular domain of the human epidermal growth factor receptor (EGFR) and inhibits EGFR signaling. It blocks ligand binding and receptor activation, which prevents the phosphorylation of downstream signaling proteins. Ac-Lys-Val-Pro-Leu-ACC can be used in pharmacology to identify new drugs that inhibit EGFR signaling pathways.

TentaGel based resin for protected peptide amides; particle size: 90 µmcapacity: 0.18 - 0.25 mmol/g

MOCA is a small peptide with anti-inflammatory properties that binds to the receptor IL-1R. It has been shown to inhibit sodium currents in neurons by binding to the Na+ channel and preventing the influx of sodium ions, which leads to an inhibition of action potentials. MOCA has also been shown to bind with high affinity to the IL-1R and blocks its activity. This inhibition of IL-1R leads to decreased production of proinflammatory cytokines.
MOCA has not been shown to have any affinity for other receptors or ligands.

A potent vasoconstrictor (Source rat, 110-123) containing disulfide bonds between Cys8-Cys13 and available as a 0.5mg vial.  
Urotensin II is a peptide involved in biological systems such as the nervous, endocrine, cardiovascular and renal and in rats it is primarily found in brainstem and spinal cord motor neurons. Like that of urotensin II-related peptide, urotensin II contains the hexapeptide -CYS-TYR-LYS-TRP-PHE-CYS- known as the core and this is crucial to its biological function.
Urotensin II can also increase the concentration of intercellular calcium through binding to its G protein coupled receptor: urotensin-II receptor which causes the activation of Protein kinase C followed by the activation of Phospholipase C.
UT-II has been shown to have a wide range of physiological effects in rats, including vasoconstriction, modulation of blood pressure, and stimulation of the release of aldosterone and vasopressin.
In addition to its physiological effects, UT-II has also been implicated in the pathogenesis of various cardiovascular and metabolic disorders, including hypertension, heart failure, and diabetes. Inhibition of UT-II signaling has been suggested as a potential therapeutic target for these conditions.

NHS-m-dPEG®(MW = 1214) is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. NHS-m-dPEG®(MW = 1214) is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

Gastrin-related peptide is a peptide that is involved in the regulation of the growth of cells. It has been shown to promote cancer cell growth, and may be involved in other cancers such as prostate cancer and neurological disorders. Gastrin related peptide is not active against normal cells, which makes it a potential therapeutic target for cancer treatment.

NPY is a peptide that is released by neurons and acts as an activator. It is also found in the central nervous system and regulates appetite, as well as other autonomic, behavioral, and endocrine functions. NPY has been shown to be an inhibitor of ion channels in the central nervous system. NPY has been shown to bind to receptors on the surface of cells, which are ligands for NPY. This binding activates or inhibits the receptor's signaling pathway. The CAS number for NPY is 1139-14-1 and it has a molecular weight of 9.6 kDa.END>

Cytochrome P450 3A4 is an enzyme that is involved in the metabolism of a wide range of compounds, including drugs and other xenobiotics. CYP3A4 can metabolize a drug from one chemical to another by adding or removing a functional group. CYP3A4 also has monooxygenase activity, meaning it can convert one compound into another using oxygen as a reactant. CYP3A4 is responsible for the metabolism of many drugs and is commonly found in humans, mice, rats, dogs and cattle.

Anti NPY (1-19) is a peptide that binds to the NPY receptor. It is an agonist of the NPY receptor, which is a G-protein coupled receptor. This peptide has been shown to activate ion channels, such as nicotinic acetylcholine receptors and glutamate receptors. Anti NPY (1-19) has also been shown to inhibit ligand binding to the NPY receptor, and may be used as a research tool for studying this receptor in cell biology.