Moduladores de enzimas
Los moduladores enzimáticos son compuestos que pueden aumentar o inhibir la actividad de las enzimas, regulando así la velocidad de las reacciones bioquímicas. Estos moduladores juegan un papel crítico en el control de las vías metabólicas, la señalización celular y diversos procesos fisiológicos. Los moduladores enzimáticos se utilizan ampliamente en la investigación y el desarrollo de fármacos para estudiar las funciones enzimáticas y desarrollar agentes terapéuticos. En CymitQuimica, ofrecemos una gama completa de moduladores enzimáticos de alta calidad para apoyar su investigación en la regulación enzimática y el descubrimiento de fármacos.
Subcategorías de "Moduladores de enzimas"
Se han encontrado 693 productos de "Moduladores de enzimas"
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Crenolanib
CAS:Inhibits type III tyrosine kinases (PDGFRα, PDGFRβ, FLT3)Fórmula:C26H29N5O2Pureza:Min. 95%Forma y color:White To Yellow SolidPeso molecular:443.54 g/molBMS 754807
CAS:A reversible inhibitor of IGF-1R kinase and insulin receptor. Has anti-growth effects in mesenchymal, epithelial and hematopoietic tumor types. Synergistic with other cytotoxic, hormonal and targeted anti-cancer therapy.
Fórmula:C23H24FN9OPureza:Min. 95%Forma y color:PowderPeso molecular:461.49 g/molAceclofenac - Bio-X ™
CAS:Acecelofenac is a non-steroidal anti-inflammatory drug that is used in the treatment of osteoarthritis, arthritis, and ankylosing spondylitis. This drug is also a cyclooxygenase inhibitor and works by inhibiting this enzyme so that pain and inflammation is reduced.Fórmula:C16H13Cl2NO4Pureza:Min. 95%Forma y color:PowderPeso molecular:354.18 g/molIrsogladine maleate - Bio-X ™
CAS:Irsogladine is a gastroprotective drug that is used for the treatment of GERD and gastric ulcers. This drug also has antioxidant properties. Irsogladine is a phosphodiesterase-4 inhibitor and increases levels of cAMP. It helps to prevent and heal damage to the stomach lining.Fórmula:C13H11Cl2N5O4Pureza:Min. 95%Forma y color:PowderPeso molecular:372.16 g/molMGCD 265
CAS:Inhibits MET, VEGFR1-3, Tie and Ron tyrosine kinases; antineoplasticFórmula:C26H20FN5O2S2Pureza:Min. 95%Peso molecular:517.60 g/molThioglycosyl Naphthalimide
CAS:Thioglycosyl Naphthalimide is a highly potent human O-GlcNAcase (hOGA) inhibitor with good selectivity against human β-N-acetylhexosaminidase B (HsHexB).Fórmula:C30H40N4O7SPureza:Min. 95%Peso molecular:600.73 g/mol(-)-Huperzine A
CAS:Acetylcholinesterase inhibitor; therapy for Alzheimer's diseaseFórmula:C15H18N2OPureza:(%) Min. 98%Forma y color:PowderPeso molecular:242.32 g/molLY 411575
CAS:Potent inhibitor of γ-secretase. LY 411575 inhibited production of amyloid β (Aβ) peptides with IC50 of 0.078 nM in vitro as well as decreased levels of Aβ40 and Aβ42 amyloids in brain of a mouse model for Alzheimer’s disease. In vitro studies confirmed that LY 411575 inhibited cleavage of Notch receptor at S3 site with IC50 of 0.39 nM, which blocked Notch activation and downstream signalling, leading to apoptosis in primary and immortalized Kaposi's sarcoma cells.Fórmula:C26H23F2N3O4Pureza:Min. 95%Forma y color:SolidPeso molecular:479.48 g/molMRK 560
CAS:γ-secretase inhibitor; reduces amyloid-β in brainÂ
Fórmula:C19H17ClF5NO4S2Pureza:Min. 95%Peso molecular:517.92 g/molGNE 6776
CAS:Specific inhibitor of the ubiquitin specific protease-7 (USP7), which is a validated deubiquitinase of the E3 ubiquitin-protein ligase MDM2. The compound inhibits the USP7 deubiquitinase activity by binding to acidic amino acid residues important for the interaction with ubiquitin. Induces tumor cell death and enhances cytotoxicity of chemotherapeutic agents.Fórmula:C20H20N4O2Pureza:Min. 95%Peso molecular:348.4 g/molIdelalisib
CAS:Idelalisib is a pharmaceutical drug that functions as a PI3Kδ inhibitor, developed through synthetic chemical processes. Its mode of action involves selectively targeting and inhibiting phosphatidylinositol 3-kinase delta (PI3Kδ), a lipid kinase that plays a crucial role in the signaling pathways responsible for cell proliferation, survival, and differentiation. By inhibiting this enzyme, Idelalisib effectively impedes pathways that are often hyperactivated in certain hematologic malignancies, thereby exerting antitumor effects.Fórmula:C22H18FN7OPureza:Min. 95%Forma y color:PowderPeso molecular:415.42 g/molSRT1720 hydrochloride
CAS:SIRT1 activatorFórmula:C25H23N7OS·xHClPureza:Min. 98 Area-%Forma y color:PowderPeso molecular:469.56 g/molAG 221
CAS:Inhibitor of isocitrate dehydrogenase 2Fórmula:C19H17F6N7OPureza:Min. 95%Forma y color:PowderPeso molecular:473.38 g/molDCC 2036
CAS:Inhibits multiple tyrosine kinases (Abl1, Src family kinases, Tie-2 and VEGFR-2)Fórmula:C30H28FN7O3Pureza:Min. 95%Forma y color:PowderPeso molecular:553.59 g/molPeiminine
CAS:Inhibitor of TGF-α, CTGF, ERK1/2, NF-κB and FasL; anti-inflammatoryFórmula:C27H43NO3Pureza:Min. 98 Area-%Peso molecular:429.64 g/molSGC AAK1 1
CAS:Dual inhibitor of the adaptor protein 2-associated kinase 1 (AAK1) and BMP2-inducible kinase (BMP2K) with IC50 values of 270 nM and 1 μM, respectively. In a recent study, SGC AAK1 1 stabilised β-catenin, inhibited phosphorylation of the AP2 complex subunit mu protein (AP2M1) and activated Wnt signalling in in vitro experiments._x000D_Fórmula:C21H25N5O3SPureza:Min. 95%Forma y color:SolidPeso molecular:427.52 g/molEbselen
CAS:Ebselen is a non-toxic organoselenium compound with antioxidant, anti-inflammatory and cytoprotective properties. Ebselen is an inhibitor of lipoxygenases, nitric oxide (NO) synthases, protein kinase C, H+/K+-ATPase, thioredoxin reductase and NADPH oxidase. Recently, ebselen has been identified by several studies as a covalent inhibitor of the main protease Mpro from coronaviruses. For the SARS-CoV-2 main protease Mpro, the IC50 value is 0.67 μM and EC50 is 4.57 μM.Fórmula:C13H9NOSePureza:Min. 98 Area-%Forma y color:PowderPeso molecular:274.18 g/molNilotinib HCl monohydrate - Bio-X ™
CAS:Nilotinib is a kinase inhibitor that is used for the treatment of Chronic Myeloid Leukemia (CML). This drug is also used for the treatment of CML that is resistant to imatinib. Nilotinib inhibits the tyrosine kinase activity of the BCR-ABL protein. It also inhibits PDGFR and c-kit.
Fórmula:C28H22F3N7O•HCl•H2OPureza:Min. 95%Forma y color:PowderPeso molecular:583.99 g/molLY 2886721
CAS:Inhibitor of BACE1 proteaseFórmula:C18H16F2N4O2SPureza:Min. 98 Area-%Forma y color:PowderPeso molecular:390.41 g/mol3-(4-Phenylbutyl)-4-propyloxetan-2-one
CAS:Cis/trans-form of GK 563 [2351820-19-2]Fórmula:C16H22O2Pureza:Min. 95%Forma y color:SolidPeso molecular:246.34 g/mol
