Fasudil, 98+%

CAS: 103745-39-7

Ref. 02-J63525

Información del producto

• Nombre: Fasudil, 98+%
• Sinónimos: HA-1077, (5-Isoquinolinesulfonyl)Homopiperazine, 1-(5-Isoquinolinesulfonyl)homopiperazine, 1-(5-Isoquinolinesulphonyl)homopiperazine, 1-(5-Isoquinolinylsulfonyl)homopiperazine, 103745-39-7, 1H-1,4-Diazepine, hexahydro-1-(5-isoquinolinylsulfonyl)-, 5-(1,4-Diazepan-1-Ylsulfonyl)Isoquinoline Dihydrochloride, 5-(1,4-Diazepan-1-Ylsulfonyl)Isoquinoline Hydrochloride (1:1), 5-(1,4-Diazepan-1-ylsulfonyl)isoquinoline, 5-[(Hexahydro-1H-1,4-diazepin-1-yl)sulfonyl]isoquinoline, At 877, Ha 1077, Hexahydro-1-(5-isoquinolinesulfonyl)-1H-1,4-diazepine, N-(5-Isoquinolinesulfonyl)-1,4-perhydrodiazepine, isoquinoline, 5-[(hexahydro-1H-1,4-diazepin-1-yl)sulfonyl]-
• CAS: 103745-39-7

Descripción

HA-1077 dihydrochloride has been shown to be a vasodilating agent as well as a potent inhibitor of Rock-2 (Rho-associated Kinase II), cGKI (cGMP-dependent protein kinase), PKA (cAMP-dependent protein kinase), MYLK, and CaMKII. Rho kinase signaling pathways are thought to cause invasion, migration, and proliferation of certain cells. Studies have shown this compound can also inhibit myosin light chain kinase in vitro and suppress cell rounding by myosin light chain phosphorylation. Mechanistic experiments report that HA-1077 inhibits vascular smooth muscle contraction by acting as a calcium channel protein inhibitor. HA-1077 dihydrochloride is an inhibitor of MSK1, PKC, PRK2 and Rsk-2. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

• Marca: Alfa Aesar By Thermo Fisher Scientific

Propiedades químicas

• Peso molecular: 327.83
• Fórmula: C₁₄H₁₇N₃O₂S
• Pureza: 98+%
• Color/Forma: Crystalline powder