Purified CHO Legumain Protein
Ref. 3D-30-2065
| 100µg | A consultar |
Información del producto
Legumain is a host cell protein (HCP) generated by CHO cells during production of biotherapeutics. This process-related impurity accumulates in the extracellular space as it is released from dead CHO cells and secreted from viable cells during cell culture. Legumain, a lysosomal protease, cleaves the asparaginyl and aspartyl bonds of therapeutic monoclonal antibodies, thus compromising their integrity, stability, and efficacy.
Purified recombinant CHO Legumain (LGMN) expressed in CHO-S cells. Contains a 6xHIS tag.
Propiedades químicas
Consulta técnica sobre: 3D-30-2065 Purified CHO Legumain Protein
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