10-[3-(4-Methyl-1-piperazinyl)propyl]-10H-phenothiazine
CAS: 84-97-9
Ref. 3D-AAA08497
5mg | 190,00 € | ||
50mg | 715,00 € |
Información del producto
- 10-(3-Methylpiperazinopropyl)phenothiazine
- 10-(γ-Methylpiperazinopropyl)phenothiazine
- 10-[3-(1-Methylpiperazin-4-yl)propyl]phenothiazine
- 10-[3-(4-Methyl-1-piperazinyl)propyl]phenothiazine
- 10-[3-(4-Methylpiperazinyl)propyl]phenothiazine
- 10-[3-(4-methylpiperazin-1-yl)propyl]-10H-phenothiazine
- 10H-Phenothiazine, 10-[3-(4-methyl-1-piperazinyl)propyl]-
- NSC 638694
- P 725
- Peragal
- Ver más sinónimos
- Perazin
- Perazine
- Pernazine
- Phenothiazine, 10-[3-(4-methyl-1-piperazinyl)propyl]-
- Psytomin
- Taxilan
10-[3-(4-Methyl-1-piperazinyl)propyl]-10H-phenothiazine is a potent inhibitor of the human p-glycoprotein (Pgp) transporter. It has been shown to inhibit the activity of PGP in vitro and in vivo, as assessed by flow assay, particle size, and titration calorimetry. 10-[3-(4-Methyl-1-piperazinyl)propyl]-10H-phenothiazine also inhibits the activity of the α7 nicotinic acetylcholine receptor. This drug may be useful for treating infectious diseases such as HIV/AIDS, hepatitis C, and malaria. 10-[3-(4-Methyl-1-piperazinyl)propyl]-10H-phenothiazine binds to crystalline cellulose and causes drug interactions with drugs that are substrates for other transporters such as p -glycoprotein.
Propiedades químicas
Consulta técnica sobre: 3D-AAA08497 10-[3-(4-Methyl-1-piperazinyl)propyl]-10H-phenothiazine
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