21-Deoxydexamethasone

CAS: 426-15-3

Ref. 3D-AAA42615

Información del producto

• Nombre: 21-Deoxydexamethasone
• Sinónimos: (11β,16α)-9-Fluoro-11,17-dihydroxy-16-methylpregna-1,4-diene-3,20-dione, 9-Fluoro-11β,17-dihydroxy-16α-methylpregna-1,4-diene-3,20-dione, Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,17-dihydroxy-16α-methyl-, Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-16-methyl-, (11β,16α)-

Descripción

21-Deoxydexamethasone is a synthetic corticosteroid that has been extracted from the adrenal cortex of animals. It is hydrolysed to deoxycorticosterone, which is then converted to corticosterone in the liver. The 21-deoxysteroid and its derivatives are used as a source of cortisone, while the 21-hydroxylated compounds are used in some synthetic glucocorticoids. Deoxycorticosterone can also be converted into hydrocortisone by β-glucuronidase. It has been shown that this drug has a high urinary excretion rate (approximately 50%), and has been analysed using spectrometry to identify conjugates. Chemical ionisation was used for identification of metabolites in urine samples, with detection limits of 0.1 ng/mL for metabolites such as 17α-dehydrodeoxycortisol and 17α-hydroxydeoxycortisol

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 376.5 g/mol
• Fórmula: C₂₂H₂₉FO₄
• Pureza: Min. 95%