dehydroergosterol (DHE)
CAS: 516-85-8
Ref. 3D-AAA51685
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Información del producto
- (22E)-Ergosta-5,7,9(11),22-tetraen-3β-ol
- (22E,24R)-Ergosta-5,7,9(11),22-tetraen-3β-ol
- (3beta,22E)-ergosta-5,7,9(11),22-tetraen-3-ol
- (3β,22E)-Ergosta-5,7,9(11),22-tetraen-3-ol
- 9(11)-Dehydroergosterol
- Dehydroergosterol
- Ergosta-5,7,9(11),22-Tetraen-3-Beta-Ol
- Ergosta-5,7,9(11),22-tetraen-3-ol, (3β,22E)-
- Ergosta-5,7,9(11),22-tetraenol
Dehydroergosterol, also known as DHE, is a cholesterol derivative that is a pro-apoptotic protein. It has been shown to inhibit the proliferation of cancer cells by binding to the ATP-binding cassette transporter and MCL-1 protein. DHE binds to cholesterol and changes its phase transition temperature from liquid to solid at physiological levels, which may be due to its anti-cancer properties. The pro-apoptotic effect of DHE was demonstrated in a model system using skin cancer cells. This compound also has been shown to have anti-cancer activity against colorectal adenocarcinoma cells in vitro and in vivo.
Propiedades químicas
Consulta técnica sobre: 3D-AAA51685 dehydroergosterol (DHE)
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