Colistin sulfate

CAS: 1264-72-8

Ref. 3D-AC20542

Información del producto

• Nombre: Colistin sulfate
• Sinónimos: Polymyxin E, Belcomycin, Colimycin sulfate, Colistin Sulphate, Colistin, Sulfat (Salz), Colistin, sulfate (salt), Colistina, Sulfato (Sal), Colistine, Sulfate (Sel), Colomycin, Colomycin syrup, N-[(1S)-3-amino-1-{[(1S,2R)-1-{[(1S)-3-amino-1-{[(3S,6S,9S,12S,15R,18S,21S)-6,9,18-tris(2-aminoethyl)-3-[(1R)-1-hydroxyethyl]-12,15-bis(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptaazacyclotricosan-21-yl]carbamoyl}propyl]carbamoyl}-2-hydroxypropyl]carbamoyl}propyl]-5-methylheptanamide, N-[(2S)-4-amino-1-{[(2S,3R)-1-{[(2S)-4-amino-1-oxo-1-{[(3S,6S,9S,12S,15R,18S,21S)-6,9,18-tris(2-aminoethyl)-3-[(1R)-1-hydroxyethyl]-12,15-bis(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptaazacyclotricosan-21-yl]amino}butan-2-yl]amino}-3-hydroxy-1-oxobutan-2-yl]amino}-1-oxobutan-2-yl]-6-methyloctanamide sulfate (1:1), N-[3-Amino-1-[[1-[[3-Amino-1-[[6,9,18-Tris(2-Aminoethyl)-3-(1-Hydroxyethyl)-12,15-Bis(2-Methylpropyl)-2,5,8,11,14,17,20-Heptaoxo-1,4,7,10,13,16,19-Heptazacyclotricos-21-Yl]Carbamoyl]Propyl]Carbamoyl]-2-Hydroxy-Propyl]Carbamoyl]Propyl]-5-Methyl-Heptanamide Sulfate, Nipoxyme, Polymyxin E sulfate, Polymyxin E, sulfate (salt)

Descripción

Colistin is a narrow-spectrum antibiotic efficient mostly against gram-negative bacteria. Colistin interacts with the outer membrane of gram-negative bacteria and induces a transfer of divalent cations of calcium and magnesium from the negatively charged phosphate groups. This causes the disruption of the outer membrane and release of lipopolysaccharides. It is commonly used against Enterobacteriaceae and Aeromonas, and none-fermentative gram-negative bacteria as well as for carbapenem-resistant Acinetobacter strains.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 1,266.73 g/mol
• Fórmula: C₅₃H₁₀₂N₁₆O₁₇S
• Pureza: Min. 77 Area-%
• Color/Forma: White Powder