3'-Des(dimethylamino)-3'-keto azithromycin
CAS: 612069-25-7
Ref. 3D-AD21086
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Información del producto
- (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-[[4,6-dideoxy-b-D-erythro-hexopyranos-3-ulos-1-yl]oxy]-13-[(2,6-dideoxy-3-C-methyl-3-O-methy l-a-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-1-oxa-6-azacyclopentadecan-15-one
3'-Des(dimethylamino)-3'-keto azithromycin is a prodrug that is hydrolyzed in vivo to the active form of azithromycin. 3'-Des(dimethylamino)-3'-keto azithromycin has an elution time of about 10 minutes on a C18 column, which is considerably longer than the 5-minute elution time for azithromycin. The chromatogram of 3'-Des(dimethylamino)-3'-keto azithromycin shows two peaks, one at 6 minutes and another at 10 minutes. These two peaks are due to impurities in the drug product, namely itraconazole and fluconazole. 3'-Des(dimethylamino)-3'-keto azithromycin has shown bioequivalence with its parent molecule, azithromycin.
Propiedades químicas
Consulta técnica sobre: 3D-AD21086 3'-Des(dimethylamino)-3'-keto azithromycin
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