7-methyl-5-nitro-1H-indazole

CAS: 75785-12-5

Ref. 3D-ADA78512

Información del producto

• Nombre: 7-methyl-5-nitro-1H-indazole
• Sinónimos: 1H-Indazole, 7-methyl-5-nitro-, 7-Methyl-5-nitro-1H-indazole

Descripción

7-Methyl-5-nitro-1H-indazole is an analog of amodiaquine, a drug used in the treatment of malaria. The compound has been shown to be hepatotoxic, which may be due to its metabolic conversion to an amino group. 7-Methyl-5-nitro-1H-indazole inhibits the growth of malaria parasites by causing DNA damage and inhibition of protein synthesis. It is metabolized by hydroxylation and excreted as a stable metabolite. This drug has been shown to be potent against malarial parasites and has anti-malarial properties that are similar to those of amodiaquine.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 177.16 g/mol
• Fórmula: C₈H₇N₃O₂
• Pureza: Min. 95%