4'-Epidaunorubicin hydrochloride

CAS: 56390-08-0

Ref. 3D-AE16714

Información del producto

• Nombre: 4'-Epidaunorubicin hydrochloride
• Sinónimos: (8S,10S)-8-Acetyl-10-[(3-amino-2,3,6-trideoxy-a-L-arabino-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-na phthacenedione hydrochloride(8S-cis)-4'-Epidaunorubicin hydrochloride4'-epi-daunomycin hydrochloride, (1S,3S)-3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-α-L-arabino-hexopyranoside hydrochloride, (8S-cis)-8-Acetyl-10-((3-amino-2,3,6-trideoxy-alpha-L-arabino-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxynaphthacene-5,12-dione hydrochloride, 4′-Epidaunorubicin hydrochloride, 4′-epi-Daunomycin hydrochloride, 5,12-Naphthacenedione, 8-acetyl-10-[(3-amino-2,3,6-trideoxy-α-<span class="text-smallcaps">L</span>-arabino-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-, hydrochloride (1:1), (8S,10S)-, 5,12-Naphthacenedione, 8-acetyl-10-[(3-amino-2,3,6-trideoxy-α-<span class="text-smallcaps">L</span>-arabino-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-, hydrochloride, (8S,10S)-, 5,12-Naphthacenedione, 8-acetyl-10-[(3-amino-2,3,6-trideoxy-α-<span class="text-smallcaps">L</span>-arabino-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-, hydrochloride, (8S-cis)-, NSC 249333, 5,12-Naphthacenedione, 8-acetyl-10-[(3-amino-2,3,6-trideoxy-α-L-arabino-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-, hydrochloride (1:1), (8S,10S)-, 5,12-Naphthacenedione, 8-acetyl-10-[(3-amino-2,3,6-trideoxy-α-L-arabino-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-, hydrochloride, (8S,10S)-, 5,12-Naphthacenedione, 8-acetyl-10-[(3-amino-2,3,6-trideoxy-α-L-arabino-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-, hydrochloride, (8S-cis)-

Descripción

4'-Epidaunorubicin hydrochloride is a water-soluble prodrug of the anthracycline drug, 4'-epidaunorubicin. It has been shown to have anti-cancer activity in cell cultures and animal models. It inhibits DNA replication by binding to DNA and preventing the unwinding of the double helix, which prevents replication. 4'-Epidaunorubicin hydrochloride can be used with aminoglycosides to prevent bacterial resistance. This drug also reduces daunorubicin and epirubicin into their active forms, and is structurally similar to these drugs. This similarity may explain why 4'-epidaunorubicin hydrochloride is effective at inhibiting protein synthesis in cells that are resistant to daunorubicin or epirubicin.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 563.98 g/mol
• Fórmula: C₂₇H₃₀ClNO₁₀
• Pureza: Min. 95%