N1-[2-Bromo-4-(trifluoromethyl)phenyl]acetamide

CAS: 175135-49-6

Ref. 3D-AHA13549

Información del producto

• Nombre: N1-[2-Bromo-4-(trifluoromethyl)phenyl]acetamide
• Sinónimos: 2'-Bromo-4'-(trifluoromethyl)acetanilide, 4-Acetamido-3-bromobenzotrifluoride, Acetamide, N-[2-bromo-4-(trifluoromethyl)phenyl]-, N-[2-bromo-4-(trifluoromethyl)phenyl]acetamide

Descripción

N1-[2-Bromo-4-(trifluoromethyl)phenyl]acetamide (NAPA) is a drug metabolite that is formed by cytochrome P450 enzymes in the liver. This metabolite has been detected in human plasma, urine and faeces. NAPA has been shown to be a major metabolite of the antidepressant drug nortriptyline. The main route of elimination for NAPA is through conjugation with glucuronic acid. High-performance liquid chromatography can be used for the separation and quantification of metabolites such as NAPA. The use of on-line introduction increases sensitivity and reduces detection time. Chromatographic profiles are often used to distinguish between different compounds with similar properties, such as NAPA and its major metabolites.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 282.06 g/mol
• Fórmula: C₉H₇BrF₃NO
• Pureza: Min. 95%