Información del producto
- Tyrphostin AG 1478
- N-(3-Chlorophenyl)-6,7-dimethoxy-4-quinazolinamine
- AG 1478
- NSC 693255
- 4-Quinazolinamine, N-(3-chlorophenyl)-6,7-dimethoxy-
InSolution AG 1478 is a tyrosine kinase inhibitor that binds to the ATP-binding site of tyrosine kinases. In vitro studies have shown that it inhibits the activation of epidermal growth factor receptor and nerve growth factor receptors, and blocks epidermal growth factor (EGF) and nerve growth factor (NGF) induced phosphorylation in mouse epidermal cells. In vivo animal studies show that this drug has an effect on axonal growth and promotes nerve regeneration. In vitro studies also show that it inhibits DNA binding activity in response to EGF or NGF.
Propiedades químicas
Consulta técnica sobre: 3D-AHA17882 InSolution AG 1478
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