Oligomycin A

CAS: 579-13-5

Ref. 3D-AO65694

Información del producto

• Nombre: Oligomycin A
• Sinónimos: (1R,2′R,4E,5′S,6S,6′S,7R,8S,10R,11R,12S,14R,15S,16R,18E,20E,22R,25S,28S,29R)-22-Ethyl-3′,4′,5′,6′-tetrahydro-7,11,14,15-tetrahydroxy-6′-[(2R)-2-hydroxypropyl]-5′,6,8,10,12,14,16,28,29-nonamethylspiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-27,2′-[2H]pyran]-3,9,13-trione, (1S,4E,5'R,6R,6'R,7S,8R,10S,11S,12R,14S,15R,16S,18E,20E,22S,25R,27S,28R,29S)-22-ethyl-7,11,14,15-tetrahydroxy-6'-[(2S)-2-hydroxypropyl]-5',6,8,10,12,14,16,28,29-nonamethyl-3',4',5',6'-tetrahydro-3H,9H,13H-spiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-27,2'-pyran]-3,9,13-trione, (1S,5'R,6R,6'R,7S,8R,10S,11S,12R,14S,15R,16S,22S,25R,27S,28R,29S)-22-ethyl-7,11,14,15-tetrahydroxy-6'-[(2S)-2-hydroxypropyl]-5',6,8,10,12,14,16,28,29-nonamethyl-3',4',5',6'-tetrahydro-3H,9H,13H-spiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-27,2'-pyran]-3,9,13-trione, Brn 5702132, Mch 32, Rp-32705, Spiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-27,2′-[2H]pyran]-3,9,13-trione, 22-ethyl-3′,4′,5′,6′-tetrahydro-7,11,14,15-tetrahydroxy-6′-[(2R)-2-hydroxypropyl]-5′,6,8,10,12,14,16,28,29-nonamethyl-, (1R,2′R,4E,5′S,6S,6′S,7R,8S,10R,11R,12S,14R,15S,16R,18E,20E,22R,25S,28S,29R)-, Spiro[2,26-dioxabicyclo[23.3.1]nonacosane-27,2′-[2H]pyran], oligomycin A deriv.

Descripción

Oligomycin A is a chemical inhibitor that binds to the α7 nicotinic acetylcholine receptor and blocks the movement of calcium ions into cells. It has been shown to be effective against wild-type strains of bacteria and pluripotent cells, as well as in studies on mitochondrial functions. Oligomycin A is a natural compound that inhibits cellular respiration by preventing the ATPase from releasing phosphate groups. Oligomycin A also specifically binds to mitochondria and inhibits mitochondrial functions. The rate constant for oligomycin A binding to the α7 nicotinic acetylcholine receptor has been determined using dinucleotide phosphate probes. This allows for an optimum concentration of oligomycin A to be determined for specific purposes, such as cytosolic calcium ion concentration or chromatographic analysis.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 791.06 g/mol
• Fórmula: C₄₅H₇₄O₁₁
• Pureza: Min. 95%
• Color/Forma: Powder