Cinobufotalin

CAS: 1108-68-5

Ref. 3D-BAA10868

Información del producto

• Nombre: Cinobufotalin
• Sinónimos: (3Beta,5Beta,15Beta,16Beta)-16-(Acetyloxy)-3,5-Dihydroxy-14,15-Epoxybufa-20,22-Dienolide, (3β,5β,15β,16β)-16-(Acetyloxy)-14,15-epoxy-3,5-dihydroxybufa-20,22-dienolide, 14,15-Epoxy-14H-cyclopenta[a]phenanthrene, bufa-20,22-dienolide deriv., 5-beta-Bufa-20,22-dienolide, 14,15-beta-epoxy-3-beta,5,16-beta-trihydroxy-, 16-acetate, 5beta-Bufa-20,22-dienolide, 14,15beta-epoxy-3beta,5,16beta-trihydroxy-, 16-acetate, 5β-Bufa-20,22-dienolide, 14,15β-epoxy-3β,5,16β-trihydroxy-, 16-acetate, Bufa-20,22-dienolide, 16-(acetyloxy)-14,15-epoxy-3,5-dihydroxy-, (3beta,5beta,15beta,16beta)-, Bufa-20,22-dienolide, 16-(acetyloxy)-14,15-epoxy-3,5-dihydroxy-, (3β,5β,15β,16β)-, Cinobufotlin, Nsc 90326

Descripción

Cinobufotalin is a natural compound that has been shown to inhibit the proliferation of cancer cells. It has been found to have an IC50 value of 4.7 nM in cell-free assays and can induce apoptosis by inhibiting the Bcl-2 protein, which prevents the release of cytochrome C from mitochondria, leading to mitochondrial membrane depolarization and activation of caspase 3. Cinobufotalin also has anti-inflammatory properties, which may be due to its inhibition of toll-like receptor 4 (TLR4) expression.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 458.54 g/mol
• Fórmula: C₂₆H₃₄O₇
• Pureza: Min. 95%