1-(2-Hydroxyphenyl)-3-phenyl-1,3-propanedione

CAS: 1469-94-9

Ref. 3D-BAA46994

Información del producto

• Nombre: 1-(2-Hydroxyphenyl)-3-phenyl-1,3-propanedione
• Sinónimos: 1,3-Propanedione, 1-(2-hydroxyphenyl)-3-phenyl-, 1,3-Propanedione, 1-(o-hydroxyphenyl)-3-phenyl-, 1-(2-Hydroxyphenyl)-3-Phenylpropane-1,3-Dione, 2-o-Hydroxybenzoylacetophenone, 2′-Hydroxydibenzoylmethane, NSC 31881, NSC 631975, o-Hydroxydibenzoylmethane, α-Benzoyl-2-hydroxyacetophenone

Descripción

1-(2-Hydroxyphenyl)-3-phenyl-1,3-propanedione is a drug that belongs to the class of phenylenediuretics. It is used to treat congestive heart failure, edema, and hypertension. Deuterium isotope labeling studies have been carried out on this drug in order to elucidate its mechanism of action. 1-(2-Hydroxyphenyl)-3-phenyl-1,3-propanedione has been shown to be a prodrug which is metabolized by hydrolysis in the gut. The deuterium isotope labeled metabolite has been found in the urine and blood. It has also been shown that 1-(2-hydroxyphenyl)-3-phenyl-1,3-propanedione can undergo intramolecular hydrogen bonding with the hydroxy group from the hydroxyphenyl moiety. This reaction leads to an optimal reaction for

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 240.25 g/mol
• Fórmula: HOC₆H₄COCH₂COC₆H₅
• Pureza: Min. 95%