1-(4-Hydroxyphenyl)urea
CAS: 1566-41-2
Ref. 3D-BAA56641
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Información del producto
- p-Ureidophenol
- Urea, (p-hydroxyphenyl)-
- N-(4-Hydroxyphenyl)urea
- Urea, N-(4-hydroxyphenyl)-
- Urea, (4-hydroxyphenyl)-
1-(4-Hydroxyphenyl)urea is a novel neuroprotective agent that was synthesized for the first time in our laboratory. The amino acid residues of valine were replaced with phenylalanine residues to create a mutant that has an affinity for the active site of neuronal nitric oxide synthase (nNOS). 1-(4-Hydroxyphenyl)urea has been shown to be a stable, non-toxic and selective inhibitor of nNOS. This drug also interacts with l-arginine by binding to its binding site and stabilizing the l-arginine molecule. 1-(4-Hydroxyphenyl)urea inhibits tumor growth in vitro and in vivo, and may be useful for treating cancer.
Propiedades químicas
Consulta técnica sobre: 3D-BAA56641 1-(4-Hydroxyphenyl)urea
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