(S)-Diethyl 2-(4-(methylamino)benzamido)pentanedioate

CAS: 2378-95-2

Ref. 3D-CAA37895

Información del producto

• Nombre: (S)-Diethyl 2-(4-(methylamino)benzamido)pentanedioate
• Sinónimos: 1,5-Diethyl N-[4-(methylamino)benzoyl]-<span class="text-smallcaps">L</span>-glutamate, <span class="text-smallcaps">L</span>-Glutamic acid, N-[4-(methylamino)benzoyl]-, 1,5-diethyl ester, <span class="text-smallcaps">L</span>-Glutamic acid, N-[4-(methylamino)benzoyl]-, diethyl ester, Diethyl N-(p-N-methylaminobenzoyl)glutamate, Diethyl N-[4-(methylamino)benzoyl]-<span class="text-smallcaps">L</span>-glutamate, Glutamic acid, N-[p-(methylamino)benzoyl]-, diethyl ester, Glutamic acid, N-[p-(methylamino)benzoyl]-, diethyl ester, <span class="text-smallcaps">L</span>-, N-(4-Methylaminobenzoyl)-L-Glutamic Acid Diethylester, N-(p-Methylaminobenzoyl)glutamic acid diethyl ester, diethyl N-[4-(methylamino)benzoyl]-L-glutamate, diethyl N-[4-(methylamino)benzoyl]glutamate, p-Methylaminobenzoylglutamic acid diethyl ester

Descripción

Diethyl 2-(4-(methylamino)benzamido)pentanedioate is a prodrug that is metabolized to (S)-diethyl 2-(4-aminobenzamido)pentanedioate, which inhibits the enzyme dihydrofolate reductase. This prevents the synthesis of tetrahydrofolate, an essential cofactor in the synthesis of nucleic acids and amino acids. The antibiotic has been shown to be active against bacteria such as Mycobacterium tuberculosis and Staphylococcus aureus, but not against mammalian cells.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 336.38 g/mol
• Fórmula: C₁₇H₂₄N₂O₅
• Pureza: Min. 95%