Información del producto
N-(3,4-Dihydroxyphenethyl)acetamide is a histamine agonist that inhibits the production of proinflammatory cytokines such as tumor necrosis factor (TNF)-α and interleukin (IL)-6 by inhibiting 5-hydroxytryptamine (5-HT) concentrations. It has been shown to inhibit the growth of HL60 cells at a concentration of 10 μM. N-(3,4-Dihydroxyphenethyl)acetamide is also able to inhibit Cox-2 enzymatic activity in vitro and has been shown to be active in vivo against chronic colitis in mice. The optimum pH for N-(3,4-dihydroxyphenethyl)acetamide is 7.0 and its Michaelis-Menten kinetics are first order. This drug also has an affinity for fatty acids and dopamine receptors, which may contribute to its anti-inflammatory effects.
Propiedades químicas
Consulta técnica sobre: 3D-CAA49412 N-(3,4-Dihydroxyphenethyl)acetamide
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