LY3177833

CAS: 1627696-51-8

Ref. 3D-CQC69651

Información del producto

• Nombre: LY3177833
• Marca: Biosynth
• Descripción: LY3177833 is a protein kinase inhibitor that binds to the ATP-binding pocket of the enzyme, inhibiting its function. LY3177833 has been shown to be effective against colon cancer cells and has been used in clinical trials. The drug was well-tolerated by patients and had no significant side effects. The efficacy of LY3177833 was demonstrated in vitro, where it inhibited the growth of colon cancer cells with an IC50 of 3 nM at 24 hours. LY3177833 also showed anti-tumor effects in a mouse xenograft model, blocking tumor growth and reducing the number of metastases. In addition, LY3177833 inhibits cellular senescence by inhibiting production of β-galactosidase enzymes and the expression of cancer-related genes.

Propiedades químicas

• Peso molecular: 309.3 g/mol
• Fórmula: C₁₆H₁₂FN₅O
• Pureza: Min. 95%