Neurokinin B (human, porcine)

Ref. 3D-CRB1000581

Información del producto

• Nombre: Neurokinin B (human, porcine)
• Sinónimos: DMHDFFVGLM-amideH-Asp-Met-His-Asp-Phe-Phe-Val-Gly-Leu-Met-NH2

Descripción

Neurokinin B (NKB) is a member of the tachykinin family of peptides that include substance P (SP), neurokinin A (NKA), endokinins and haemokinins. NKB is encoded by TAC3 in humans and Tac2 in rodents and along with the neuropeptide kisspeptin plays an essential role as gatekeeper of puberty.NKB plays a stimulatory role in luteinising hormone (LH) release in a number of species, likely mediated via the secretion of gonadotropin-releasing hormone (GnRH) in a kisspeptin-dependent manner (NKB appears to play a critical role in the control of kisspeptin release). NKB may contribute to the regulation of reproductive functions by metabolic cues. NKB binds with highest affinity to the G-protein coupled neurokinin-3 receptor NK3R also known as tachykinin receptor 3 (TACR3)

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 1,209.5 g/mol