Información del producto
Nombre:Biotin-DAG Peptide
Sinónimos:
- [Cyc(1,9)]Biot-CDAGRKQKC-OHBiotin-CDAGRKQKC-acid
- (Disulfide bridge: Cys1 - Cys9)Biotin-Cys-Asp-Ala-Gly-Arg-Lys-Gln-Lys-Cys-OH
- (D isulfide bridge: Cys1 - Cys9 )a-Calcitonin gene-related peptide (mous
Marca:Biosynth
Descripción:Cyclic DAG peptide targets connective tissue growth factor (CTGF/CCN2), present in the extracellular matrix, endothelial cells and overexpressed in several brain diseases. CTGF is a matricellular protein that acts as a regulator of several cellular functions, including cell adhesion, migration, mitogenesis, differentiation, and survival. CTGF is up regulated in Alzheimer's disease, Parkinson's disease, brain injury, glioblastoma, and cerebral infarction.DAG peptide has been shown to home to the brain in mouse models of glioblastoma, traumatic brain injury, and Parkinson's disease when exogenously delivered, making it an attractive target for the treatment of glioblastoma. DAG may be of use as a tool to enhance delivery of therapeutics and imaging agents to sites of brain diseases.
Aviso:Nuestros productos están destinados únicamente para uso en laboratorio. Para cualquier otro uso, por favor contáctenos.
Propiedades químicas
Peso molecular:1,231.5 g/mol