GLP-1 (9-36) amide
Ref. 3D-CRB1000982
| 1mg | 271,00 € | ||
| 500µg | 198,00 € |
Información del producto
- H-EGTFTSDVSSYLEGQAAKEFIAWLVKGR-NH2EGTFTSDVSSYLEGQAAKEFIAWLVKGR-amideH-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln- Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp
Natural cleavage product of GLP-1 which, unlike GLP-1, does not affect either insulin secretion or glucose homeostasis. GLP-1(9-36) has low affinity for, and acts as an antagonist to, the GLP-1 receptor.GLP-1 (9-36) does however display unique biological activities such as beneficial cardiovascular effects and reducing the production of reactive oxygen species (ROS). GLP-1 (9-36) also exerts important physiological effects on neuronal plasticity in the hippocampus, and inhibits chemokine-induced migration of human CD4-positive lymphocytes.GLP-1 (9-36) is formed from the breakdown of biologically active but highly unstable GLP-1 (7-36) amide by the ubiquitous serine protease, dipeptidyl peptidase-IV (DPP-IV).
Propiedades químicas
Consulta técnica sobre: 3D-CRB1000982 GLP-1 (9-36) amide
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