AD01
Ref. 3D-CRB1001113
| 1mg | 271,00 € | ||
| 500µg | 198,00 € |
Información del producto
- H-IRQQPRDPPTETLELEVSPDPAS-OHIRQQPRDPPTETLELEVSPDPAS-acidH-Ile-Arg-Gln-Gln-Pro-Arg-Asp-Pro-Pro-Thr-Glu-Thr-Leu-Glu-Leu-Glu-Val-Ser- Pro-Asp-Pro-Ala-Ser-OH
AD01 is a derivative of the FK506 binding protein-like (FKBPL), and exerts potent anti-angiogenic activity in vitro and in vivo to control tumour growth. Recent studies have shown that AD-01 inhibits Rac-1 activity, and up-regulates RhoA and the actin binding proteins, profilin and vinculin. In this way, the anti-angiogenic proteins, FKBPL, and AD-01, offer a promising and alternative approach for targeting both CD44 positive tumours and vasculature networks. Recent clinical studies have shown that AD01 and other FKBPL-based peptides may offer an alternative for targeting treatment-resistant breast cancer stem cells.
Propiedades químicas
Consulta técnica sobre: 3D-CRB1001113 AD01
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