Cyclo(-RGDyK)

Ref. 3D-CRB1001169

Información del producto

• Nombre: Cyclo(-RGDyK)
• Sinónimos: [LacN(0,5)]RGD(dY)K
• Marca: Biosynth
• Descripción: The cyclic pentapeptide cyclo(-Arg-Gly-Asp-d-Phe-Lys-) is a highly potent and selective inhibitor for the alphavβ3 integrin receptor. A related compound, cyclo(-Arg-Gly-Asp-d-Phe-Val), is a promising anti-cancer drug candidate- it inhibits angiogenesis and induces apoptosis in vascular cells.Cyclic RGD-containing peptides are selective antagonists of integrins, proteins that play important roles in cell-cell and cell-matrix interactions. In a suitably labelled form, these peptides may serve as useful tools for diagnostic imaging and peptide targeted therapy of some types of cancer.

Propiedades químicas

• Peso molecular: 619.3 g/mol