Lys-[Des-Arg 9] Bradykinin Heavy
Ref. 3D-CRB1300684
25nMol | 452,00 € |
Información del producto
- H-KRPPGF^SPF-OH
Lys-des-Arg(9) bradykinin is a metabolite of des-Arg(9)kinin and its production is increased upon inflammation. Lys-des-Arg(9) bradykinin acts on the bradykinin B(1) receptor as a potent and highly selective receptor agonist.The bradykinin receptor B1Rs is a heterotrimeric G-protein coupled receptor which regulates migration of microglia and T cells. The expression of the B(1) receptor is induced in various inflammatory conditions, and may play an important role in modulating cardiovascular function.The phenylalanine-residue at positions 6 of this peptide is isotopically labelled with carbon-13 (9) and nitrogen-15 (1), giving this peptide a mass increase of 10 compared to the unlabelled peptide.
Propiedades químicas
Consulta técnica sobre: 3D-CRB1300684 Lys-[Des-Arg 9] Bradykinin Heavy
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