N-(2-(1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide
CAS: 253168-86-4
Ref. 3D-DKA16886
| 100mg | A consultar | ||
| 250mg | A consultar | ||
| 500mg | A consultar |
Información del producto
Apremilast is a prodrug that is converted in vivo to its active form. It inhibits the production of tumor necrosis factor-α (TNF-α) and interleukin-1β (IL-1β), which are inflammatory cytokines. Apremilast is also an inhibitor of phosphodiesterase 4 (PDE4), which degrades cyclic adenosine monophosphate (cAMP). This drug has been shown to be effective in the treatment of arthritis, with pain relief after two weeks and improvement in joint mobility after four weeks. Apremilast is available as a racemate, with enantiomers having different pharmacological properties. The most potent form of apremilast is the S(-) enantiomer, which has been shown to be more potent than the R(+) enantiomer for inhibition of TNF-α and IL-1β.
Propiedades químicas
Consulta técnica sobre: 3D-DKA16886 N-(2-(1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide
Si desea solicitar un presupuesto o realizar un pedido, por favor añada los productos deseados a su carrito y solicite un presupuesto o pedido desde el carrito. Es más rápido, más barato, y podrá beneficiarse de los descuentos y las ventajas disponibles.
