Información del producto
BAY 59-9435 is a highly selective small molecule activator of PPARβ/δ. BAY 59-9435 has been shown to increase mitochondrial biogenesis and fatty acid oxidation in vitro, as well as improve insulin sensitivity in vivo. These effects are mediated by the activation of PPARβ/δ, which is an important regulator of metabolic processes. The activation of PPARβ/δ also decreases inflammatory gene expression such as toll-like receptors, camp levels, and sphingosine kinase. The mechanism by which BAY 59-9435 increases mitochondrial biogenesis may involve upregulation of transcription factor peroxisome proliferator-activated receptor gamma coactivator 1α (PGC1α) and other genes that encode proteins involved in mitochondrial biogenesis.
Propiedades químicas
Consulta técnica sobre: 3D-EBB05921 BAY 59-9435
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