Información del producto
Ethyl 4-(4-nitrophenyl)-2,4-dioxobutanoate is an inhibitor of cytosolic carbonic anhydrase (CA). CA is a zinc-dependent enzyme that catalyzes the conversion of CO2 to HCO3-. This inhibition prevents the conversion of bicarbonate ions to carbon dioxide and thus reduces the intracellular pH. Ethyl 4-(4-nitrophenyl)-2,4-dioxobutanoate has been shown to inhibit primary tumor growth in mice and squamous cell carcinoma in human erythrocytes. The isoforms of CA targeted by this agent are not well characterized, but it has been shown to inhibit both cytosolic and mitochondrial forms.
Propiedades químicas
Consulta técnica sobre: 3D-ECA80856 Ethyl 4-(4-nitrophenyl)-2,4-dioxobutanoate
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