Cefixime

CAS: 79350-37-1

Ref. 3D-EDA35037

Información del producto

• Nombre: Cefixime
• Sinónimos: (-)-Cefixim, (6R,7R)-7-(2-(2-Amino-4-thiazolyl)gloxylamido)-8-oxo-3-vinyl-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7(square)-(Z)-(O-(carboxymethyl)oxime)-trihydrate, (6R,7R)-7-({(2-amino-1,3-thiazol-4-yl)[(carboxymethoxy)imino]acetyl}amino)-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, (6R,7R)-7-({(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(carboxymethoxy)imino]acetyl}amino)-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, (6R,7R)-7-({(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(carboxymethoxy)imino]acetyl}amino)-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid trihydrate, (6R,7R)-7-[[(2Z)-2-(2-Amino-4-thiazolyl)-2-[(carboxymethoxy)imino]acetyl]amino]-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2-amino-4-thiazolyl)[(carboxymethoxy)imino]acetyl]amino]-3-ethenyl-8-oxo-, [6R-[6α,7α(Z)]]-, 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2-amino-4-thiazolyl)[(carboxymethoxy)imino]acetyl]amino]-3-ethenyl-8-oxo-, [6R-[6α,7β(Z)]]-, 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-(2-amino-4-thiazolyl)[(carboxymethoxy)imino]acetyl]amino]-3-ethenyl-8-oxo-, (6R,7R)-, 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-[(carboxymethoxy)imino]acetyl]amino]-3-ethenyl-8-oxo-, (6R,7R)-, Cefexy, Cefixime main-ring, Cefiximine, Cefixoral, Cefoceb, Cefspan, Ceftas, Cephoral, Cl 284635, Fixitil, Fk 027, Fr 17027, Hifen, Loprax, Oroken, Suprax, Suprax (antibiotic), Taxim-O, Unixime, Ximacef

Descripción

Cefixime is a penicillin-binding protein inhibitor that binds to the 50S ribosomal subunit. It is used for the treatment of infectious diseases caused by bacteria. Cefixime has been shown to have an optimum concentration of 2-4 micrograms/mL in human plasma. The oral bioavailability of cefixime is approximately 30% and it has an elimination half-life of 1.5 hours. The drug is metabolized primarily through oxidation by cytochrome P450 enzymes, which are induced by other drugs, such as erythromycin and clarithromycin, or enzyme inducers such as phenobarbital, rifampin, or carbamazepine. Cefixime inhibits bacterial growth through competitive inhibition with penicillin-binding proteins (PBPs), which are required for bacterial cell wall synthesis and protein synthesis.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 453.45 g/mol
• Fórmula: C₁₆H₁₅N₅O₇S₂
• Pureza: Min. 95%
• Color/Forma: Powder