2-(4-((2,4-Dioxothiazolidin-5-yl)methyl)phenoxy)acetic acid
CAS: 179087-93-5
Ref. 3D-EHA08793
| 1g | A consultar |
Información del producto
2-(4-((2,4-Dioxothiazolidin-5-yl)methyl)phenoxy)acetic acid (BMS-201038) is a novel drug that can be used to treat type 2 diabetes. It has been shown to reduce insulin resistance and increase insulin sensitivity in rodents when it is administered orally. BMS-201038 binds to the hydroxyl group of the active site of the enzyme inositol phosphatase, which regulates intracellular signaling pathways and glucose levels. This drug also has a hydroxyl group that may react with nucleophiles such as water or thiols, which may lead to its hydrolysis.
BMS-201038 also has two trifluoromethyl groups that could be oxidized by cytochrome P450 enzymes, leading to the formation of metabolites with different activities than those found in the parent compound.
Propiedades químicas
Consulta técnica sobre: 3D-EHA08793 2-(4-((2,4-Dioxothiazolidin-5-yl)methyl)phenoxy)acetic acid
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