4-Methylumbelliferyl N,N',N'',N'''-tetraacetyl-b-D-chitotetraoside

CAS: 53643-14-4

Ref. 3D-EM04831

Información del producto

• Nombre: 4-Methylumbelliferyl N,N',N'',N'''-tetraacetyl-b-D-chitotetraoside
• Sinónimos: GlcNAc1-b-4GlcNAc1-b-4GlcNAc1-b-4GlcNAc1-b-4MU
• Marca: Biosynth
• Descripción: 4-Methylumbelliferyl N,N',N'',N'''-tetraacetyl-beta-D-chitotetraoside is a fluorogenic substrate for chitinase. After enzymatic cleaveage, free 4-methylumbelliferone (also known as hymecromone) is released, exhibiting blue fluorescence upon excitation with UV light. The strongest fluorescence of 4-methylumbelliferone requires deprotonation of the hydroxyl group (thus requires alkaline pH), with a maximal fluorescence intensity obtained with excitation at 350 to 370 nm and emission at 440 to 470 nm. The use of 4-methylumbelliferyl N,N',N'',N'''-tetraacetyl-beta-D-chitotetraosideas a substrate for measuring the chitinase activity is used for fungal infection detection and Gaucher disease screening.

Propiedades químicas

• Peso molecular: 988.94 g/mol
• Fórmula: C₄₂H₆₀N₄O₂₃
• Pureza: Min. 95%
• Color/Forma: Powder