Secreted Phospholipase A2-IIA, human, recombinant
Ref. 3D-ENZ-290
| 2µg | 136,00 € | ||
| 10µg | 317,00 € |
Información del producto
- PLA2G2A Human MOM1 PLA2 PLA2B PLA2L PLA2S PLAS1 sPLA2 Phospholipase A2 Membrane Associated EC 3.1.1.4 Phosphatidylcholine 2-Acylhydrolase Group IIA Phospholipase A2 GIIC sPLA2 Non-Pancreatic Secretory Phospholipase A2 NPS-PLA2 sPLA2-IIA PL
The secreted phospholipase A2-IIA (sPLA2-IIA) is a proinflammatory enzyme that catalyzes the hydrolysis of glycerophospholipids at the sn-2 position. This enzyme is expressed by neutrophils, macrophages, and other cell types. It is also found in lipocalin and can be secreted into the extracellular environment. sPLA2-IIA has been shown to have oncogenic properties in cells transfected with an oncogene, which may be due to its ability to promote arachidonic acid release from membrane phospholipids and to induce synthesis of inflammatory mediators such as prostaglandins and leukotrienes.
Propiedades químicas
Consulta técnica sobre: 3D-ENZ-290 Secreted Phospholipase A2-IIA, human, recombinant
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