1-(2-Chloro-4-fluorobenzyl)-5-methyl-3-nitro-1H-pyrazole
CAS: 1004643-55-3
Ref. 3D-EQB64355
1g | Descatalogado | ||
50mg | Descatalogado | ||
100mg | Descatalogado | ||
250mg | Descatalogado | ||
500mg | Descatalogado |
Información del producto
- 1-[(2-Chloro-4-fluorophenyl)methyl]-5-methyl-3-nitro-1H-pyrazole
- 1H-Pyrazole, 1-[(2-chloro-4-fluorophenyl)methyl]-5-methyl-3-nitro-
1-(2-Chloro-4-fluorobenzyl)-5-methyl-3-nitro-1H-pyrazole is a pyrazole analog that has been shown to have cox-2 inhibitory effects. It also binds to the receptor for pyrazole, and it is a potent agonist at this receptor. 1-(2-Chloro-4-fluorobenzyl)-5-methyl-3-nitro--1H--pyrazole inhibits the production of prostaglandin E2, which may be due to its ability to bind to the Cox enzyme and prevent it from synthesizing prostaglandins. The synthesis of 1-(2--chloro--4--fluorobenzyl)-5--methyl--3--nitro--1H--pyrazole starts with 2,6,8,-trimethylpyridine as a starting material. This compound undergoes nitration using nitric