GLPG 1837

CAS: 1654725-02-6

Ref. 3D-ERC72502

Información del producto

• Nombre: GLPG 1837
• CAS: 1654725-02-6

Descripción

GLPG 1837 is a novel amide that modulates autophagy, an intracellular degradation process that plays a key role in the maintenance of cellular homeostasis. GLPG 1837 has been shown to inhibit autophagy in human primary cells and to protect against lipopolysaccharide (LPS)-induced lung injury. This compound also inhibits chloride conductance and produces bronchodilation in a rat model of asthma. The structural biology of this molecule has been elucidated by X-ray crystallography and NMR spectroscopy. GLPG 1837 is being developed as a potential treatment for chronic obstructive pulmonary disease (COPD).

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 348.42 g/mol
• Fórmula: C₁₆H₂₀N₄O₃S
• Pureza: Min. 95%