5-Amino-1H-imidazole-4-carboxamide

CAS: 360-97-4

Ref. 3D-FA09803

Información del producto

• Nombre: 5-Amino-1H-imidazole-4-carboxamide
• Sinónimos: 5-Aminoimidazole-4-carboxamide
• Marca: Biosynth

Descripción

5-Amino-1H-imidazole-4-carboxamide is a potent inhibitor of inosine monophosphate dehydrogenase (IMPDH). This enzyme converts inosine 5'-monophosphate (IMP) to xanthosine 5'-monophosphate (XMP) and is essential for the synthesis of purines. By inhibiting IMPDH, 5-amino-1H-imidazole-4-carboxamide prevents the formation of XMP, which leads to the depletion of purines, thereby inhibiting DNA synthesis. In addition to its role as an anti-inflammatory agent, this drug has been shown to reduce disease activity in bowel disease patients by reducing nitrate reductase activity. The molecule has also been shown to inhibit protein kinases such as PKC and MAPK/ERK kinases.

Propiedades químicas

• Peso molecular: 126.12 g/mol
• Fórmula: C₄H₆N₄O
• Pureza: Min. 95%
• Color/Forma: Powder