Ac-DL-Phe-pNA

CAS: 19746-42-0

Ref. 3D-FA110699

Información del producto

• Nombre: Ac-DL-Phe-pNA
• Sinónimos: 2-Acetamido-N-(4-nitrophenyl)-3-phenylpropanamide, 2-Acetylamino-N-(4-nitro-phenyl)-3-phenyl-propionamide, Benzenepropanamide, α-(acetylamino)-N-(4-nitrophenyl)-, Hydrocinnamanilide, α-acetamido-4′-nitro-, <span class="text-smallcaps">DL</span>-, α-(Acetylamino)-N-(4-nitrophenyl)benzenepropanamide

Descripción

Ac-DL-Phe-pNA is a synthetic derivative of the natural substrate Ac-Lys-pNA. It binds to the active site of serine proteases and blocks the release of their active form, which results in inhibition of collagen synthesis. The reaction is reversible and it can be hydrolyzed by chymotrypsin or elastase. Ac-DL-Phe-pNA has been shown to inhibit protein-protein interactions between epimastigotes and extracellular matrix proteins, leading to cell death. This compound has also been found to have an optimum pH of 6.5, which is neutral.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 327.33 g/mol
• Fórmula: C₁₇H₁₇N₃O₄
• Pureza: Min. 95%