Ac-Phe-Gly-pNA
CAS: 34336-99-7
Ref. 3D-FA110700
1g | 2.453,00 € | ||
50mg | 317,00 € | ||
100mg | 460,00 € | ||
250mg | 874,00 € | ||
500mg | 1.409,00 € |
Información del producto
- N-Acetylphenylalanylglycine 4-nitroanilide
- Nacphe-gly-4-NA
- Glycinamide, N-acetyl-L-phenylalanyl-N-(4-nitrophenyl)-
- Nalpha-acetyl-N-{[(4-nitrophenyl)amino]acetyl}-L-phenylalaninamide
Ac-Phe-Gly-pNA is a peptidyl prodrug that has been shown to have proteolytic activity against cells of the malignant phenotype. Ac-Phe-Gly-pNA is converted to an active form by serine proteases, which are found on the surface of trophozoites and in cancerous cells. The sequence of Ac-Phe-Gly-pNA is homologous with a protein found in Giardia lamblia, and it has been shown to be active against this parasite. Ac-Phe-Gly-pNA can also be detected with fluorogenic substrates and aminopeptidase activity.
Propiedades químicas
Consulta técnica sobre: 3D-FA110700 Ac-Phe-Gly-pNA
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