4-Amino-N-(2-phenylethyl)benzenesulfonamide

CAS: 587850-67-7

Ref. 3D-FA113793

Información del producto

• Nombre: 4-Amino-N-(2-phenylethyl)benzenesulfonamide

Descripción

4-Amino-N-(2-phenylethyl)benzenesulfonamide (4APBS) is a histone deacetylase inhibitor. It has been shown to inhibit the histone methyltransferase activity of EZH2, which is important for regulating gene expression, in cells treated with 4APBS. This inhibition leads to increased levels of the transcriptional coactivator β-catenin and reduced levels of tumor suppressor genes. These changes ultimately lead to an increase in cancer cell proliferation and decreased apoptosis. 4APBS also interacts with hormone receptors that are found on the surface of cells and can regulate cellular functions such as proliferation, differentiation, or apoptosis.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 276.36 g/mol
• Fórmula: C₁₄H₁₆N₂O₂S
• Pureza: Min. 95%
• Color/Forma: Off-White Powder
• InChI: InChI=1S/C14H16N2O2S/c15-13-6-8-14(9-7-13)19(17,18)16-11-10-12-4-2-1-3-5-12/h1-9,16H,10-11,15H2
• Clave InChI: InChIKey=BYWZPUPRVIECEC-UHFFFAOYSA-N
• SMILES: Nc1ccc(S(=O)(=O)NCCc2ccccc2)cc1