4-(1-Adamantyl)benzenesulfonyl chloride

CAS: 144174-50-5

Ref. 3D-FA117188

Información del producto

• Nombre: 4-(1-Adamantyl)benzenesulfonyl chloride

Descripción

4-Adamantylbenzenesulfonyl chloride is a conformationally constrained analogue of the natural product 1,2-dihydrobenzofuran. It is a potent inhibitor of human cytochrome P450 enzymes, with Ki values in the range of 2 to 10 nM. 4-Adamantylbenzenesulfonyl chloride binds to the active site of cytochrome P450 and blocks access to substrate, thereby inhibiting the metabolism of drugs such as phenytoin and propranolol. 4-Adamantylbenzenesulfonyl chloride can be used as a probe for investigating enzyme activity in vitro or in vivo.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 310.84 g/mol
• Fórmula: C₁₆H₁₉ClO₂S
• Pureza: Min. 95%
• Color/Forma: Powder