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2-Azaspiro[3.4]octane
CAS: 665-41-8
Ref. 3D-FA157490
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Información del producto
2-Azaspiro[3.4]octane is an annulated bicyclic molecule that contains a cyclopentane ring and a cyclobutane carboxylate group. The synthesis of 2-azaspiro[3.4]octane starts from the commercially available cyclopentene, which is converted to the corresponding allyl bromide by reaction with allyl bromide in the presence of base. This product can also be synthesized diastereoselectively from 2-iodoazaspiro[3.4]octane and 1,1′-carbonyldiimidazole in the presence of base. The experimental procedure for this synthesis starts with an acidic work up followed by purification by chromatography on silica gel eluting with dichloromethane:ethyl acetate (5:1).
2-Azaspiro[3.4]octane has been shown to have minimal toxicity in rats
Propiedades químicas
Consulta técnica sobre: 3D-FA157490 2-Azaspiro[3.4]octane
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