Información del producto
Nombre:Alternariol-9-methyl ether
Marca:Biosynth
Descripción:Alternariol-9-methyl ether is a natural compound that has been shown to have significant cytotoxic effects on murine hepatoma cells. This compound also synergizes with anti-retroviral drugs and has been found to be capable of inducing apoptosis in HIV-infected T cells at low concentrations. Alternariol-9-methyl ether is structurally related to the polycyclic aromatic hydrocarbons, such as alternariol, which are only weakly toxic to mice but are potent pro-apoptotic proteins when bound covalently to DNA. Structural analysis of this compound revealed that it inhibits the binding of a pro-apoptotic protein (Bid) to its target site on dsDNA, preventing Bid from initiating apoptosis. It is thought that this effect may be responsible for its synergistic interaction with active antiretroviral therapy.
Aviso:Nuestros productos están destinados únicamente para uso en laboratorio. Para cualquier otro uso, por favor contáctenos.
Propiedades químicas
Peso molecular:272.25 g/mol
Fórmula:C15H12O5
Pureza:Min. 95%
Color/Forma:Powder
InChI:InChI=1S/C15H12O5/c1-7-3-8(16)4-12-13(7)10-5-9(19-2)6-11(17)14(10)15(18)20-12/h3-6,16-17H,1-2H3
Clave InChI:InChIKey=LCSDQFNUYFTXMT-UHFFFAOYSA-N
SMILES:COc1cc(O)c2c(=O)oc3cc(O)cc(C)c3c2c1
Consulta técnica sobre: Alternariol-9-methyl ether
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