13-cisAcitretin

CAS: 69427-46-9

Ref. 3D-FA17201

Información del producto

• Nombre: 13-cisAcitretin
• Sinónimos: 9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoic acidisoacitretin13-cis-etretinisoetretinro 13-7652, (2Z,4E,6E,8E)-9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoic acid, 13-cis-Acitretin, 13-cis-Etretin, 2,4,6,8-Nonatetraenoic acid, 9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-, (2Z,4E,6E,8E)-, 2,4,6,8-Nonatetraenoic acid, 9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-, (Z,E,E,E)-, 2,4,6,8-Nonatetraenoicacid,9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-,(Z,E,E,E)-, A.(2Z,4E,6E,8E)-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoic acid, Isoacitretin, Isoetretin, Ro 13-7652

Descripción

Acitretin is a synthetic retinoid. It has been shown to be a potent inhibitor of the nuclear receptor co-repressor, which may account for its anti-psoriatic effects. Acitretin is also an active inhibitor of the enzyme squamous cell carcinoma (SCC), which may account for its antitumor activity. Oral administration of acitretin leads to minimal toxicity and increased bioavailability, as well as a high rate constant in humans. This drug has been shown to have minimal toxicity and is more effective than etretinate or acitretin in the treatment of psoriasis, with less side effects such as bowel disease and cancer.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 326.43 g/mol
• Fórmula: C₂₁H₂₆O₃
• Pureza: Min. 95%
• InChI: InChI=1S/C21H26O3/c1-14(8-7-9-15(2)12-21(22)23)10-11-19-16(3)13-20(24-6)18(5)17(19)4/h7-13H,1-6H3,(H,22,23)/b9-7+,11-10+,14-8+,15-12-
• Clave InChI: InChIKey=IHUNBGSDBOWDMA-UGOGCBOOSA-N
• SMILES: COc1cc(C)c(/C=C/C(C)=C/C=C/C(C)=C\C(=O)O)c(C)c1C