Adarotene

CAS: 496868-77-0

Ref. 3D-FA175281

Información del producto

• Nombre: Adarotene
• Sinónimos: (2E)-3-(4'-Hydroxy-3'-tricyclo[3.3.1.13,7]dec-1-yl[1,1'-biphenyl]-4-yl)-2-propenoic acid, (2E)-3-(4′-Hydroxy-3′-tricyclo[3.3.1.1^3,7]dec-1-yl[1,1′-biphenyl]-4-yl)-2-propenoic acid, (E)-3-[4-[3-(1-Adamantyl)-4-hydroxyphenyl]phenyl]prop-2-enoic acid, 2-Propenoic acid, 3-(4′-hydroxy-3′-tricyclo[3.3.1.1^3,7]dec-1-yl[1,1′-biphenyl]-4-yl)-, (2E)-, 3-(4'-Hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid, St 1926

Descripción

Adarotene is a cytosolic calcium ionophore that has potent inducers of chemiluminescence. It is a synthetic retinoid that binds to the nuclear retinoid receptor and induces transcription of genes. Adarotene has been shown to inhibit cancer cell proliferation, induce apoptosis, and act as an anti-cancer compound. The polymerase chain reaction (PCR) technique has been used to measure adarotene concentration in t-cell lymphomas. Adarotene is toxic to cells and causes cellular physiology changes by altering mitochondrial membrane potential.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 374.47 g/mol
• Fórmula: C₂₅H₂₆O₃
• Pureza: Min. 95%
• InChI: InChI=1S/C25H26O3/c26-23-7-6-21(20-4-1-16(2-5-20)3-8-24(27)28)12-22(23)25-13-17-9-18(14-25)11-19(10-17)15-25/h1-8,12,17-19,26H,9-11,13-15H2,(H,27,28)/b8-3+
• Clave InChI: InChIKey=QAWBIEIZDDIEMW-FPYGCLRLSA-N
• SMILES: O=C(O)/C=C/c1ccc(-c2ccc(O)c(C34CC5CC(CC(C5)C3)C4)c2)cc1