2-Amino-5-[(3,4,5-trimethoxyphenyl)methyl]-4(1H)-pyrimidinone

CAS: 92440-76-1

Ref. 3D-FA17603

Información del producto

• Nombre: 2-Amino-5-[(3,4,5-trimethoxyphenyl)methyl]-4(1H)-pyrimidinone
• Sinónimos: 2-Amino-5-(3,4,5-trimethoxybenzyl)-4-pyrimidinol, 2-Amino-5-[(3,4,5-trimethoxyphenyl)methyl]-1H-pyrimidin-6-one, 2-Amino-5-[(3,4,5-trimethoxyphenyl)methyl]-4(3H)-pyrimidinone, 2-amino-5-(3,4,5-trimethoxybenzyl)pyrimidin-4(3H)-one, 4(1H)-Pyrimidinone, 2-amino-5-[(3,4,5-trimethoxyphenyl)methyl]-, 4(3H)-Pyrimidinone, 2-amino-5-[(3,4,5-trimethoxyphenyl)methyl]-, 4-Pyrimidinol, 2-amino-5-(3,4,5-trimethoxybenzyl)-

Descripción

2-Amino-5-[(3,4,5-trimethoxyphenyl)methyl]-4(1H)-pyrimidinone (2APTMP) is a nitrogen-containing compound that is an analog of the pyrimidine nucleotide uridine. It has been shown to have antihypertensive activity in animals and humans. 2APTMP inhibits collagen synthesis and increases the degradation of type I procollagen by inhibiting lysyl hydroxylase activity. It may also inhibit DNA replication, as it binds to dna replication proteins and inhibits enzyme activity. This compound also has anticancer activities against human endometrial carcinoma cells in vitro and mycobacterium avium complex in vivo. 2APTMP does not have pesticidal activity or pesticidal effects on insects such as Drosophila melanogaster.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 291.3 g/mol
• Fórmula: C₁₄H₁₇N₃O₄
• Pureza: Min. 95%
• InChI: InChI=1S/C14H17N3O4/c1-19-10-5-8(6-11(20-2)12(10)21-3)4-9-7-16-14(15)17-13(9)18/h5-7H,4H2,1-3H3,(H3,15,16,17,18)
• Clave InChI: InChIKey=ZKFZTBRMADDRMK-UHFFFAOYSA-N
• SMILES: COc1cc(Cc2cnc(N)[nH]c2=O)cc(OC)c1OC