Información del producto
- (2S)-2-Acetamido-3-(1H-indol-3-yl)propanoic acid
- (S)-N-Acetyltryptophan
- <span class="text-smallcaps">L</span>-N-Acetyltryptophan
- <span class="text-smallcaps">L</span>-Tryptophan, N-acetyl-
- Ac-L-Trp-OH
- Acetyl-<span class="text-smallcaps">L</span>-tryptophan
- Acetyltryptophan
- N-Acetyl-<span class="text-smallcaps">L</span>-tryptophan
- N-Acetyl-L-Tryptophan
- N-acetyltryptophan
- Ver más sinónimos
- N-α-Acetyl-L-Tryptophan
- NSC 90726
- Tryptophan, N-acetyl-, <span class="text-smallcaps">L</span>-
N-Acetyl-L-tryptophan is a neuroprotective agent that binds to the group p2 receptor for neurokinin-1 (NK-1) and inhibits the apoptosis pathway. It is used in the treatment of Parkinson's disease, Alzheimer's disease, and Huntington's disease. N-Acetyl-L-tryptophan has been shown to inhibit inflammatory lesions in rats with experimental autoimmune encephalomyelitis, an animal model of multiple sclerosis. This drug also interacts with toll-like receptor 4 (TLR4), which activates downstream signaling cascades involving NFκB, MAP kinase, and JAK/STAT pathways. The molecular docking analysis revealed that N-acetyl tryptophan binds to specific sites on TLR4 and prevents its activation by preventing binding of LPS.
Propiedades químicas
Consulta técnica sobre: 3D-FA37435 N-Acetyl-L-tryptophan
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