Amino-naphthalen-1-yl-acetic acid

CAS: 97611-60-4

Ref. 3D-FA50897

Información del producto

• Nombre: Amino-naphthalen-1-yl-acetic acid
• Sinónimos: 2-Amino-2-(naphthalen-4-yl)acetic acid, 1-Naphthaleneacetic Acid, Alpha-Amino-, Amino(1-naphthyl)acetic acid

Descripción

Amino-naphthalen-1-yl-acetic acid is a non-nucleoside inhibitor of HIV reverse transcriptase. Amino-naphthalen-1-yl-acetic acid binds to the active site of HIV reverse transcriptase and inhibits the enzyme's ability to make RNA copies of viral DNA. It has been shown that amino-naphthalen-1-yl-acetic acid is more potent than thioacetamide in inhibiting HIV reverse transcriptase. Amino-naphthalen-1-yl acetic acid also has a mutant type selectivity and is active against wild type and mutant strains of HIV. Molecular modeling studies have shown that amino naphthalen 1 yl acetic acid binds to the enzyme's active site, which may be due to its similarity with thioacetamide, a known substrate for this enzyme.

• Marca: Biosynth

Propiedades químicas

• Peso molecular: 201.22 g/mol
• Fórmula: C₁₂H₁₁NO₂
• Pureza: Min. 95%
• InChI: InChI=1S/C12H11NO2/c13-11(12(14)15)10-7-3-5-8-4-1-2-6-9(8)10/h1-7,11H,13H2,(H,14,15)
• Clave InChI: InChIKey=SCDZHZMVNQDLCM-UHFFFAOYSA-N
• SMILES: NC(C(=O)O)c1cccc2ccccc12