1-Amino-1-cycloheptane carboxylic acid
CAS: 6949-77-5
Ref. 3D-FA59790
1g | A consultar | ||
2g | A consultar | ||
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Información del producto
- 1-Amino-1-Cycloheptanecarboxylic Acid
- 1-Amino-cycloheptanecarboxylic acid
- 1-Aminocycloheptane-1-Carboxylic Acid
- 1-Azaniumylcycloheptane-1-carboxylate
- Acide 1-aminocycloheptanecarboxylique
- Cycloheptanecarboxylic Acid, 1-Amino-
- NSC 22849
1-Amino-1-cycloheptane carboxylic acid is a tetrapeptide and tripeptide that has been shown to inhibit histone deacetylase. This inhibition prevents the removal of acetyl groups from lysine residues in the N-terminal tails of histones, which alters chromatin structure and gene expression. 1-Amino-1-cycloheptane carboxylic acid has been shown to be effective against chronic myeloid leukemia (CML) cells in vitro and in vivo. The CML cells are characterized by a chromosome translocation that creates an oncogenic fusion protein. This fusion protein is the target of 1-amino-1-cycloheptane carboxylic acid, which inhibits its function by blocking the action of two enzymes involved in the synthesis of this protein.
Propiedades químicas
Consulta técnica sobre: 3D-FA59790 1-Amino-1-cycloheptane carboxylic acid
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