Información del producto
Nombre:2-Aminochrysene
Marca:Biosynth
Descripción:2-Aminochrysene is a chemical that binds to DNA and causes a genotoxic effect. It has been shown to be carcinogenic to rats and is carcinogenic in humans. 2-Aminochrysene is metabolized by conjugation with glucuronic acid or glutathione, which are found in the liver, kidney, and other tissues. The binding constants for 2-aminochrysene were measured using the calf thymus DNA as a substrate and amines as ligands. Transfer of 2-aminochrysene from the plasma membrane to the cytosol was observed in cells treated with nitrous oxide (NO). The cytosolic enzyme binding assay showed that 2-aminochrysene binds to the S9 protein of hepatic microsomes.2-Aminochrysene has also been shown to inhibit phospholipase A2 activity, which may be due to its ability to bind to the enzyme's active site.
Aviso:Nuestros productos están destinados únicamente para uso en laboratorio. Para cualquier otro uso, por favor contáctenos.
Propiedades químicas
Peso molecular:243.3 g/mol
Fórmula:C18H13N
Pureza:Min. 95%
Color/Forma:Yellow Powder
InChI:InChI=1S/C18H13N/c19-14-7-10-16-13(11-14)6-9-17-15-4-2-1-3-12(15)5-8-18(16)17/h1-11H,19H2
Clave InChI:InChIKey=KSDIHKMNSYWRFB-UHFFFAOYSA-N
SMILES:Nc1ccc2c(ccc3c4ccccc4ccc23)c1
Consulta técnica sobre: 2-Aminochrysene
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